CTCF Promotes Muscle Differentiation by Modulating the Activity of Myogenic Regulatory Factors
نویسندگان
چکیده
منابع مشابه
Inhibition of mechanosensitive cation channels inhibits myogenic differentiation by suppressing the expression of myogenic regulatory factors and caspase-3 activity.
Mechanosensitive cation channels (MSC) are ubiquitous in eukaryotic cell types. However, the physiological functions of MSC in several tissues remain in question. In this study we have investigated the role of MSC in skeletal myogenesis. Treatment of C2C12 myoblasts with gadolinium ions (MSC blocker) inhibited myotube formation and the myogenic index in differentiation medium (DM). The enzymati...
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Heparin and heparan sulfate mediated basic fibroblast growth factor (bFGF) signaling plays an important role in skeletal muscle homeostasis by maintaining a balance between proliferation and differentiation of muscle progenitor cells. In this study we investigate the role of a synthetic mimic of heparin, poly(sodium-4-styrenesulfonate) (PSS), on myogenic differentiation of C2C12 cells. Exogenou...
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Jing Zhang E-mail: [email protected] Zheng-zhou Ying E-mail: [email protected] Zhong-lin Tang Corresponding author. Fax/ Tel: +86 01062813822 Email addresses: [email protected] Liang-qi Long Co-corresponding author E-mail: [email protected] Kui Li E-mail: [email protected] To whom correspondence should be addressed: Zhong-lin Tang, Ph.D, Department of Gen...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2011
ISSN: 0021-9258
DOI: 10.1074/jbc.m110.164574